EFELos Angeles, US

American actor Bob Saget, best known for his lead role in the television comedy series "Full House," died on Sunday at the age of 65.

Saget, who was born in Philadelphia in 1956, was found unresponsive in a hotel room in Orlando, the Orange County Sheriff's Office in Florida said.

"The man was identified as Robert Saget & pronounced deceased on scene. Detectives found no signs of foul play or drug use in this case," it added.

Saget had performed on Saturday night at the Ponte Vedra Concert Hall in Jacksonville as part of his comedy tour.

"Loved tonight's show @PV_ConcertHall in Jacksonville. Appreciative audience," the actor tweeted after the show alongside a photo. "I had no idea I did a 2 hr set tonight. I'm happily addicted again to this shit."