efe-epaBy David Villafranca Los Angeles

A completely synchronized and "in tune" orchestra where a single discordant note can ruin everything. That is how "Home Economics" star Karla Souza described to EFE the spark needed to create good comedy on her return to it after several years of dramatic roles, including "Nosotros los Nobles" (2013) and "How to Get Away with Murder" (2014-2020).

Souza on Wednesday will make her debut on ABC's "Home Economics," a comedy series also starring Topher Grace, Caitlin McGee, Jimmy Tatro and Sasheer Zamata.

"Home Economics" focuses on three brothers: a writer in his spare time (Grace), a millionaire (Tatro) and an out-of-work therapist (McGee).

Intertwined among the misadventures, jealousies and awkward incidents involving the three brothers is Marina (Souza), the Mexican wife of Grace's character who, from an ironic but also pragmatic perspective, watches the train wreck of her in-laws almost always with a glass of wine in her hand.